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how does viagara/cialis work?

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Cumar-Labasuul
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Re: how does viagara/cialis work?

Postby Cumar-Labasuul » Sun Nov 13, 2011 3:21 pm

Ask Heff :lol:

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Kukri
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Re: how does viagara/cialis work?

Postby Kukri » Sun Nov 13, 2011 3:25 pm

salool wrote:Kukri, artificial flag followed by heartattack is a big turn off. ;)




Heart attack comes from chemical viagra. There are herbal ones that are eco-friendly with no health risk. lol

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Re: how does viagara/cialis work?

Postby SultanOrder » Sun Nov 13, 2011 3:26 pm

Uhm no, haven't gotten to the "monastery" just yet, I guess I'm on the "journey" but not really, sorta like being in a car and not moving but the car is, I guess the car is age and time, you get me :?

I'm sure the monastery is great if the journey is meaningful and I'm the first to arrive ;)

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Re: how does viagara/cialis work?

Postby quark » Sun Nov 13, 2011 3:28 pm

Kukri wrote:
Awe wrote::lol: :lol: :lol: :lol: Stop jerking off and ull be fine u dont need this shit.


:lol:


Image

:clap:

:lol: :lol: :lol:

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salool
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Re: how does viagara/cialis work?

Postby salool » Sun Nov 13, 2011 3:52 pm

Kukri wrote:
salool wrote:Kukri, artificial flag followed by heartattack is a big turn off. ;)




Heart attack comes from chemical viagra. There are herbal ones that are eco-friendly with no health risk. lol


wow you're so well informed about these kinda things. ;)

Joks aside, i think whoever seeks help is brave.To many are silent about their problems and never get help even if their marriages breaks because of it.There is no shame admiting it when ur body fails you and it's not ur foult.
But if the guy is jaad chewer he deserve whatver happens to him and all i'm gonna say to that guy is:MAC SONKOR!

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qoraxeey
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Re: how does viagara/cialis work?

Postby qoraxeey » Sun Nov 13, 2011 3:52 pm

PO

u are young man .. why do u care how it works

:lol: :down:

Lord Diplock
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Re: how does viagara/cialis work?

Postby Lord Diplock » Sun Nov 13, 2011 4:07 pm

They work this way: they increase the amount of blood going to your you know who and crucially keep the blood there. Potentially it could last for days especially the Cialis one. Young guys use it to impress one-nighters, I mean, they can go on and on. I recommend U take it once and see it for yourself. :up: :lol: :lol: ;) ....I cannot take, I have a weak heart. :cry: :lol: :lol: :lol: and am single :lol: :lol: :lol:

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Re: how does viagara/cialis work?

Postby bareento » Sun Nov 13, 2011 4:14 pm

who needs viagra?
harari khat and red googara ...mashallah the result is strong and lasting ages 8-)

B.

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salool
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Re: how does viagara/cialis work?

Postby salool » Sun Nov 13, 2011 4:26 pm

bareento wrote:who needs viagra?
harari khat and red googara ...mashallah the result is strong and lasting ages 8-)

B.


Khaaf rabak.

It's well known that most men who chew suffer from early E and impotence..so please keep ur khuraafat to urself :|

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Bro
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Re: how does viagara/cialis work?

Postby Bro » Sun Nov 13, 2011 4:52 pm

Kukri wrote:
Awe wrote::lol: :lol: :lol: :lol: Stop jerking off and ull be fine u dont need this shit.


:lol:


Image

:clap:


:lol: :lol:

bareento
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Re: how does viagara/cialis work?

Postby bareento » Sun Nov 13, 2011 4:57 pm

salool wrote:
bareento wrote:who needs viagra?
harari khat and red googara ...mashallah the result is strong and lasting ages 8-)

B.


Khaaf rabak.

It's well known that most men who chew suffer from early E and impotence..so please keep ur khuraafat to urself :|


:D

salool/helwa give a try to harari khat :up:

B.

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Talo alle udaa
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Re: how does viagara/cialis work?

Postby Talo alle udaa » Sun Nov 13, 2011 6:16 pm

The mechanism of action of Sildenafil (Viagra) is one of enzyme kinetics. In the lumen of blood vessels are endothelial cells. Acyteylcholine binds to a 7-transmembrane protein receptor, activating the Phospholipase C pathway. Phospholipase C splits a molecule of Innositol Triphosphate into Diacyl glycerol and IP3. IP3 goes into the endoplasmic reticulum to release stores of Calcium Ion channels. The increased Calcium bumbs into a protein called Calmodulin, which when activated activates Nitric Oxide synthase. Nitric Oxide synthase catalyzes the formation of Nitric Oxide (NO), which leaves the endothelial cell lining the walls of blood vessels into near by smooth muscle cells lining the outer wall of the blood vessel. The receptor of the NO is also an anzyme, that catalyzes the formation of Cyclic GMP (cGMP). Now cGMP activates protein kinase G (PKG), whose ultimate outcome is the dissociation of the actin-myosin complex of smooth muscle cells leading to increased smooth muscle relaxation. Normally the cGMP formed is hydrolyzed by a cGMP phosphodiesterase.

All that Viagra does, is to prolong the half life of the cGMP molecule, so that it can activate more PKG, which leads to more smooth muslce relaxation of blood vessel walls leading to greater blood flow to ischiocavernosus muscles of the penis and hence greater erection time.

Sildenafil has greater affinity for PDE-5, a type of phosphodiesterase found in the smooth muscle walls of erectile tissue.


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