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doctormed
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Product info: Diabetes
Actoplus Met (Metformin And Pioglitazone) is a combination of two oral diabetes medicines that help control blood sugar levels.
Actoplus Met is for people with type 2 diabetes who do not use daily insulin injections. This medication is not for treating type 1 diabetes.
Actoplus Met may also be used for purposes other than those listed in this medication guide.

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What should I discuss with my healthcare provider before taking Actoplus Met?

Some people have developed a life-threatening condition called lactic acidosis while taking Actoplus Met. Get emergency medical help if you have any of these symptoms of lactic acidosis: weakness, increasing sleepiness, slow heart rate, cold feeling, muscle pain, shortness of breath, stomach pain, feeling light-headed, and fainting.

You may be more likely to develop lactic acidosis if you have congestive heart failure.

Do not use Actoplus Met if you have kidney disease, or if you are in a state of diabetic ketoacidosis (call your doctor for treatment with insulin).

If you have certain conditions, you may need a dose adjustment or special tests to safely take Actoplus Met. Before taking this medication, tell your doctor if you have::

congestive heart failure or heart disease;

a history of heart attack or stroke;

liver disease; or

eye problems caused by diabetes.

If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking Actoplus Met. Be sure the surgeon knows ahead of time that you are using this medication.

Taking certain oral diabetes medications may increase your risk of serious heart problems. However, not treating your diabetes can damage your heart and other organs. Talk to your doctor about the risks and benefits of treating your diabetes with Actoplus Met.

Some women using Actoplus Met have started having menstrual periods, even after not having a period for a long time due to a medical condition. You may be able to get pregnant if your periods restart. Talk with your doctor about the need for birth control.

FDA pregnancy category C. It is not known whether Actoplus Met is harmful to an unborn baby. Before taking this medication, tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether metformin or pioglitazone passes into *** milk or if it could harm a nursing baby. Do not take Actoplus Met without telling your doctor if you are ***-feeding a baby. Older adults may have a higher risk of developing lactic acidosis. Talk with your doctor about your individual risk.

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